The Bonizzoni Research Group

Summary schemes of research plans Fundamental interactions in the binding of small molecules to PAMAM dendrimers Applications: solubilization of hydrophobic aromatics and drug discovery applications Small models for PAMAM dendrimers Analytical applications: multivariate detection and pattern-based recognition

We study the chemistry of reversible intermolecular interactions in water. We use methods typically associated with organic and analytical chemistry, with a special focus on optical spectroscopy. We also make our own tools if the right ones are not already available; for instance, we synthesize fluorescent dyes with multiple electrostatic charges, and other small molecules used to simulate the behavior of large polyelectrolytes in solution.

We use what we learn to construct chemical systems with emergent functions, such as molecular-level chemical sensors, drug delivery vehicles, and nanoscopic reaction vessels.